High potency factor VIII concentrates.

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منابع مشابه

6 Factor VIII Concentrates, Factor VIII/von Willebrand Factor Concentrates, Factor IX Concentrates, Activated Prothrombin Complex Concentrates

6.5 Range of Application, Dosage, Mode of Administration 6.5.1 General Information 6.5.2 Indications for Replacement Therapy Using Factor Concentrates 6.5.3 Dosage, Mode of Administration 6.5.3.1 Replacement in Children with Hemophilia A, B or von Willebrand Syndrome 6.5.3.2 Replacement in Adults with Hemophilia A, B or von Willebrand Syndrome 6.5.3.3 Indications and Recommended Doses for Treat...

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6 Factor VIII Concentrates, Factor VIII/von Willebrand Factor Concentrates, Factor IX Concentrates, Activated Prothrombin Complex Concentrates.

6.5 Range of Application, Dosage, Mode of Administration 6.5.1 General Information 6.5.2 Indications for Replacement Therapy Using Factor Concentrates 6.5.3 Dosage, Mode of Administration 6.5.3.1 Replacement in Children with Hemophilia A, B or von Willebrand Syndrome 6.5.3.2 Replacement in Adults with Hemophilia A, B or von Willebrand Syndrome 6.5.3.3 Indications and Recommended Doses for Treat...

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Recommendations on the potency labelling of factor VIII and factor IX concentrates.

Project members: AR Hubbard, J Dodt, T Lee, K Mertens, R Seitz, A Srivastava, M Weinstein National Institute for Biological Standards and Control, Potters Bar, UK; Paul-EhrlichInstitut, Langen, Germany; Center for Biologics Evaluation & Research/Food and Drug Administration, Rockville MD, USA; Sanquin Blood Supply Foundation, Amsterdam, The Netherlands; Christian Medical College, Vellore, India.

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Recombinant clotting factor VIII concentrates: Heterogeneity and high-purity evaluation.

Factor VIII is an important glycoprotein involved in hemostasis. Insertion of expression vectors containing either the full-length cDNA sequence of human factor VIII (FLrFVIII) or B-domain deleted (BDDrFVIII) into mammalian cell lines results in the production of recombinant factor VIII (rFVIII) for therapeutic usage. Three commercially available rFVIII concentrates (Advate, Helixate NexGen and...

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Anti-A haemagglutinins in factor VIII concentrates.

Experimental evidence has been obtained that cryoprecipitation concentrates anti-A in mixtures of group O and group A plasma by a mechanism that does not operate in group O plasma alone. It has been concluded that the anti-A/A polysaccharide complex is less soluble during cryoprecipitation than anti-A immunoglobulin, and this complex dissociates to give free anti-A when the cryoprecipitate is r...

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ژورنال

عنوان ژورنال: BMJ

سال: 1992

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.304.6822.319-b